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CRC 1340

Matrix in Vision
Spokesperson Prof. Dr. Bernd Hamm
Coordinator Jana Möckel
Contact Details +49 30 450 627324

Charité – Universitätsmedizin Berlin
Campus Virchow Klinikum
Augustenburger Platz 1
13353 Berlin

Research Programme

“Matrix in Vision” Collaborative Research Centre (CRC 1340), funded by the Deutsche Forschungsgemeinschaft (DFG), aims at using inflammation as a pathologic case in point to experimentally investigate how the different ECM components might be targeted for in vivo imaging. This will be done for a variety of clinically relevant inflammatory disease entities. The experimental methods to be used include ex vivo and in vivo examinations with imaging probes, biophysical mechanical test procedures, biochemical analysis, histology, as well as molecule- and element-specific microscopy.

The CRC 1340 combines biological molecular methods in radiology with new biophysical insights into the role of mechanical tissue parameters in the development of disease, thus enabling 1) the investigation of the interaction of molecular imaging probes with the ECM; 2) the investigation of new imaging approaches using various types of magnetic nanoparticles and gadolinium-based imaging probes; and 3) multiscale quantification of mechanical structural elements of the ECM, ranging from microscopic collagen and glycosaminoglycan networks to macroscopic mechanical parameters investigated by clinical diagnostic elastography.

Gender Equality in the CRC 1340

The CRC 1340 has organised the following equal opportunities events:

  • Rotunda Habilis – 21.11.2018 – Panel discussion
  • Grant writing workshop for female PostDocs – 04.-05.04.2019 – Workshop
  • Unconscious Bias – 08.11.2019 – Workshop
  • Presentation workshop for women – 05.-06.12.2019 – Workshop
  • Sovereignty training for women – 10.-12.11.2020 – Online workshop

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